Found 7 matching trials
A Pharmacokinetics Study of the Effects of GSK2118436 on Warfarin, the Effects of Ketoconazole and Gemfibrozil on GSK2118436, and the Effects of Repeat Doses of GSK2118436 in Subjects With BRAF Mutant Solid Tumors PHASE1 GSK2118436 is an orally administered, potent and selective small molecule B...
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GSK Investigational Site
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Effects of Dabrafenib on the Single Dose Pharmacokinetics (PK) of Rosuvastatin and Midazolam PHASE1 This is an open-label, multi-center, fixed sequence study in subjects with ...
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GSK Investigational Site
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Enhancing Radioiodine Incorporation Into Radio Iodine Refractory Thyroid Cancers With MAPK Inhibition PHASE2 This is a prospective interventional trial that aims to restore iodine inco...
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Dabrafenib and/or Trametinib Rollover Study PHASE4 This study is to provide access for patients who are receiving treatment wi...
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Honor Health Research Institute
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Investigate Safety, Pharmacokinetics and Pharmacodynamics of GSK2118436 & GSK1120212 PHASE2 This was an open-label, dose escalation study to investigate the safety, ph...
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Novartis Investigative Site
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Precision Medicine Trial Based on Molecular Matching Therapy for Patients With Standard Treatment Exhaustion PHASE2 The main purpose of this study is to explore the feasibility of selecting t...
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Tianjin Medical Unversity Second Hospital
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A Phase 1/2a Study of IMM-1-104 in Participants With Advanced or Metastatic Solid Tumors PHASE1 This is an open-label, dose-exploration and expansion study to determine th...
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Active Not Recruiting
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